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Polynucleotides

Regenerative skin booster for brighter, firmer, healthier-looking skin

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Treatment summary

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Polynucleotides (PN-HPT) are highly purified DNA fragments sourced from fish. When gently injected into the skin they “wake up” fibroblast cells—the skin’s natural builders—so they can make fresh collagen and elastin. The result is firmer, smoother, healthier-looking skin that quite literally regenerates itself from within.

How the Treatment Works

  • Deep hydration first: PN-HPT forms a soft, three-dimensional gel that immediately attracts water, giving instant bounce and glow.
  • Cellular repair next: As the gel naturally breaks down it feeds skin cells with energy-rich building blocks, encouraging new collagen, elastin and extra-cellular matrix for long-term resilience.
  • Future-proofing: By restoring an ideal environment for fibroblasts the treatment “primes” your skin, so you respond even better to other procedures like lasers, peels or filler.

Why Clients Love It

  • 100 % biocompatible and naturally re-absorbed by the body.
  • Revives dull, tired complexions with a luminous ‘glass-skin’ finish.
  • Targets fine lines, uneven tone, dark circles, acne marks and sun damage in one go.
  • No artificial volume—just healthier, rejuvenated skin.

Where Can It Be Used?

Face, neck, décolletage, under-eye area, hands, and even the scalp or intimate zones where skin quality needs a boost.

What Results Can I Expect?

Expect skin that looks firmer, smoother and more radiant, with dark circles softened and dry areas noticeably more hydrated. Early changes show within three weeks, while best results appear after your course is complete and can last around six to nine months.

Safety & Downtime

The procedure is classed as low-risk. You may see mild redness, pinpoint swelling or small bruises for a day or two; normal activities can usually resume straight away.

Frequently Asked Questions

What exactly are polynucleotides?

They are purified pieces of DNA that tell your skin cells to repair and regenerate—think of them as a “software update” for tired tissue.

How is this different from filler or Skin Booster injections?

Filler and boosters mainly add water or volume; polynucleotides switch on your own collagen-building machinery, so results look natural and get better over time.

Does the procedure hurt?

Most people feel only slight stings from the tiny needles. We can apply numbing cream or use a cannula for extra comfort.

How many sessions will I need?

A standard course is three to four visits about three weeks apart, followed by one refresher every six to nine months.

When will I see a change?

Skin looks dewy within days thanks to the hydration gel. Firmer, smoother texture builds gradually from week three onward as new collagen forms.

Will I look puffy afterwards?

Little bumps flatten within 24–48 hours. You can wear mineral makeup after 12 hours if you wish.

Is it safe for darker skin tones?

Yes. Polynucleotides actually help balance excess pigment, so they are safe for all Fitzpatrick types.

Can I combine this with other treatments?

Absolutely. Using polynucleotides first can make laser, radio-frequency or filler sessions work better and last longer thanks to the skin-priming effect.

What our clients say

Rosie has simply changed my life. Her expertise and attention to detail ​have not only visually transformed my appearance but have equally given me back my confidence.

From the first conversation with Rosie I felt reassured that I would be given the best treatment. However I never expected such exceptional aftercare too.

I had a deep scar and the treatment results have reduced me to tears. There is no hard sell, just professional advice delivered in a caring and calm environment.

My advice is to book a consultation with Rosie. You too can then share your positive experience and transformations.”

Evette, Warwickshire

​Rosie always listens carefully to what I think I need, before she makes any suggestions. She has introduced me to new products by giving me her honest opinion and I have always been thrilled with the result.

I’ve been to another practitioner in the UK and one in South Africa, but Rosie’s expertise is beyond compare.

– Ms S, Oxford

I cannot thank Rosie enough for the healthier and younger looking image that I now have; my confidence and positive outlook have soared along with my looks.

I am so thrilled with Rosie’s work that I would never dream of letting another practitioner touch my skin – her results are nothing short of miraculous!

– JJ, Warwickshire

To me, the results already look like a transformation – in the subtlest way of course. I love the fact that my eyebrows have lifted, and I love the new pout. I never thought I would do this kind of treatment – I thought I would age gracefully without help! – But I’m so happy I did.

– Rachel, Oxfordshire

Once you’ve been to Rosie, I can assure you, you’ll never want to go anywhere else for treatments ever again. I would not hesitate to recommend her to anyone who wants to look more vibrant and confident.​

​– Maxine, Leamington Spa

Book your appointment.

We provide a private and confidential environment so that you can get expert advice and find out all about your treatment options.

We are more than happy to assist with any initial questions you may have, to help you make an informed decision about your treatment journey.

​You’ll be warmly welcomed at our Oxfordshire and Warwickshire clinics.

Rosie Cooper

Site Disclaimer: there is no guarantee of specific treatment results. Results can be subjective and may vary. Treatments are only availble to over 18s and we reserve the right to ask for proof of age before performing any treatment

Tel: 07788 951153 Email: info@rosiecooperaesthetics.com


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